AP13230PU-N WISP2 (Center) antibody

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0.4 ml / €370.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human WISP2

Product Description for WISP2

Rabbit anti Human WISP2.
Properties: (Center)
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for WISP2

Product Category Primary Antibodies
Target Category
Quantity 0.4 ml
Synonyms CCN5, CT58, CTGF-L, CTGFL, Connective tissue growth factor-like protein, Connective tissue growth factor-related protein 58, UNQ228/PRO261, WISP-2, WNT1-inducible-signaling pathway protein 2
Presentation Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O76076
Immunogen:
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human WISP2.
GeneID:
8839
Property Center
Application ELISA: 1/1,000.
Western blotting: 1/100 - 1/500.
Flow cytometry.
Background Wisp2 a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. Wisp2 lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.
Caution This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Concentration 2.0 mg/mL
General Readings
  1. Clark, H.F., et al., Genome Res. 13(10):2265-2270 (2003).
  2. Banerjee, S., et al., Neoplasia 5(1):63-73 (2003).
  3. Kumar, S., et al., J. Biol. Chem. 274(24):17123-17131 (1999).
  4. Pennica, D., et al., Proc. Natl. Acad. Sci. U.S.A. 95(25):14717-14722 (1998).
  5. Saxena, N., et al., Mol. Cell. Biochem. 228 (1-2), 99-104 (2001).
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Buffer System:
PBS with 0.09% (W/V) sodium azide
State:
Liquid purified Ig
Purified
Specificity
Specificity:
This antibody reacts to WISP2.
Species:
Human.
Gene ID 8839

Accessory Products

Proteins and/or Positive Controls

Proteins for WISP2 (8 products)

Catalog No. Species Pres. Purity   Source  

WISP2

WISP2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

WISP2

WISP2 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
20 µg / €139.00
  OriGene Technologies, Inc.

WISP2

WISP2 Human Purified > 95 % by SDS-PAGE gel and HPLC analyses E. coli
  OriGene Technologies GmbH

WISP2

WISP2 Human Purified > 95 % by SDS-PAGE gel and HPLC analyses E. coli
  OriGene Technologies GmbH

WISP2

WISP2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

WISP2

WISP2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

WISP2

WISP2 Human
  Abnova Taiwan Corp.

WISP2

WISP2 Human
  Abnova Taiwan Corp.

Positive controls for WISP2 (3 products)

Catalog No. Species Pres. Purity   Source  

WISP2 293T Cell Transient Overexpression Lysate(Denatured)

WISP2 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

WISP2 Lysate

Western Blot: WISP2 Lysate [NBL1-17858] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for WISP2
  Novus Biologicals Inc.

WISP2 overexpression lysate

WISP2 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.
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