NB100-94440 WNV Env antibody

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Rabbit anti Virus WNV Env


Product Description for WNV Env

Rabbit anti Virus WNV Env.
Presentation: Purified
Product is tested for Enzyme Immunoassay.

Properties for WNV Env

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Purified
Reactivity Vi
Applications E
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Rabbit anti-WNV Envelope protein polyclonal antibody was raised against a synthetic peptide corresponding to 15 amino acids near the center of the WNV Envelope protein (Genbank accession no. NP_776014).
Add. information Research Areas: Immunology
Application ELISA, This polyclonal antibody can be used for the detection of the WNV Envelope protein in ELISA. It will detect 10 ng of free peptide at 1 ug/ml., ELISA,
Background West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state (reviewed in 1). Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins (1). While the viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway (2), the highly glycosylated envelope protein plays a major role for WNV entry into target cells as this entry can be inhibited by using a recombinant domain III from the envelope glycoprotein (3). The WNV receptor has recently been identified as alpha v beta 3 integrin (4).
Storage Store at 4C. Do not freeze.
IgG purified
Buffer System:
0.02% Sodium Azide
IgG purified

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