discontinued

AP26086PU-N ZBTB8 (C-term) antibody

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0.1 mg / €360.00

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Rabbit anti Human, Mouse ZBTB8

AP26086PU-N

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Product Description for ZBTB8

Rabbit anti Human, Mouse ZBTB8.
Properties: (C-term)
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for ZBTB8

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms BOZ-F1, ZBTB8A, Zinc finger and BTB domain-containing protein 8
Presentation Aff - Purified
Reactivity Hu, Ms
Applications E, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q96BR9
Immunogen:
17 amino acid peptide near the carboxy terminus of human ZBTB8
GeneID:
653121
Property C-term
Control peptide AP26086CP-N
Application ELISA.
Western blot: 1-2 µg/ml.
Positive control: Mouse Spleen Tissue Lysate.
Background The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB8, also known as BOZ-F1, is present in multiple tissues, and is highly expressed in the cytoplasm of the placenta. While little is known about ZBTB8, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Another ZBTB proteins, ZBTB7A, has been implicated as a proto-oncogene whose overexpression contributes to malignancy in breast cancer, suggesting that ZBTB8 may act as a transcriptional repressor or be involved in tumorigenesis.
General Readings
  1. Filion GJ, Zhenilo S, Salozhin S, Yamada D, Prokhortchouk E, Defossez PA. A family of human zinc finger proteins that bind methylated DNA and repress transcription. Mol Cell Biol. 2006 Jan;26(1):169-81. PubMed PMID: 16354688. (Free PMC Article available, 8 images available)
  2. Qu H, Qu D, Chen F, Zhang Z, Liu B, Liu H. ZBTB7 overexpression contributes to malignancy in breast cancer. Cancer Invest. 2010 Jul;28(6):672-8. doi: 10.3109/07357901003631007. PubMed PMID: 20394500.
Storage Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography purified via peptide column
Buffer System:
PBS containing 0.02% sodium azide
State:
Liquid Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, mouse
Specificity
Specificity:
This antibody detects ZBTB8 at C-term.
At least two isoforms of ZBTB8 are known to exist; this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other ZBTB protein family members.
Gene ID 653121

Accessory Products

Proteins and/or Positive Controls

Positive controls for ZBTB8 (1 products)

Catalog No. Species Pres. Purity   Source  

ZBTB8A overexpression lysate

ZBTB8A overexpression lysate
0.1 mg / €280.00
  OriGene Technologies, Inc.
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