AP10432PU-N Human IgD antibody

Search for all "Human IgD"

1 ml / €270.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Product Description for Human IgD

Presentation: Purified
Product is tested for Paraffin Sections.

Properties for Human IgD

Product Category Secondary Antibodies
Target Category
Quantity 1 ml
Synonyms Human Immunoglobulin D
Presentation Purified
Reactivity Hu
Applications P
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Purified IgD
Application Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Sections: 1/50-1/200
Pretreatment of deperaffinized tissue with heat-induced epitope retrieval is recommended.
Use Polymer anti Mouse/Rabbit immunoglobulin as a detection system.
Positive Control: Lymph node.
Background Little is known about the normal function of IgD, and few clinical signs or symptoms are associated with its absence. Individuals with low or absent levels of IgD do not appear unusually predisposed to infections. In mice, IgD may substitute for some functions of IgM when IgM is absent. IgD is expressed on peripheral B cells and is used as a pan B cell marker.
Storage Store the antibody undiluted at 2-8°C. 
Shelf life: one year from despatch.
Format
State:
Liquid purified ig fraction with 0.2% BSA and 15mM Sodium Azide.
Purified
Specificity
Specificity:
Anti-IgD antibody reacts with surface immunoglobulin IgD delta chains. This antibody is useful when identifying leukemias, plasmacytomas, and B-cell lineage derived lymphomas (in particular Marginal Zone Lymphoma). Cytoplasmic staining is easily identified on paraffin tissue. Surface immunoglobulin is difficult to demonstrate on paraffin sections but can be demonstrated on frozen sections.
Cellular Localization: Cytoplasmic.
Species:
Human.
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