Product Description for TLR5
Mouse anti Canine, Human, Mouse TLR5 19D759.2.
Properties: (700-800)
Presentation: Alexa Fluor 488
Product is tested for Flow Cytometry.
Properties: (700-800)
Presentation: Alexa Fluor 488
Product is tested for Flow Cytometry.
Properties for TLR5
| Product Category | Primary Antibodies |
|---|---|
| Target Category | |
| Quantity | 0.1 mg |
| Synonyms | TIL3, Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3 |
| Presentation | Alexa Fluor 488 |
| Reactivity | Can, Hu, Ms |
| Applications | F |
| Clonality | Monoclonal |
| Clone | 19D759.2 |
| Host | Mouse |
| Isotype | IgG2a |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | Acris Antibodies GmbH |
| Material safety datasheet | MSDS for Monoclonal Antibodies (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Property | 700-800 |
| Application | Flow cytometry (Cell Surface). Flow cytometry (Intracellular): 1-2 µg/10e6 cells. |
| Background | The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLRs characterized so far activate the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway. Thirteen homologs of TLRs (TLR1-13) have been described. Toll-like receptor 5 (TLR5) expression is upregulated following exposure to bacteria or to the TLR5 agonist, flagellin. Gram-negative bacteria, stimulate monocyte/macrophage cells in a TLR5-specific, CD14-independent manner. The TLR5 receptor thus appears to be the principal means by which the innate immune system recognizes flagellated bacterial pathogens. |
| Concentration | 0.5 mg/ml |
| General Readings |
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| Storage | Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: six months from despatch. |
| Format |
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| Species Reactivity |
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| Specificity |
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| FocusOn and Reviews |
Accessory Products
Proteins and/or Positive Controls
Proteins for TLR5 (4 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00007100-Q01-10 |
TLR5 |
||||||
|
Human | 12.5% SDS-PAGE Stained with Coomassie Blue. | in vitro transl. | ||||
| Abnova Taiwan Corp. | |||||||
| H00007100-Q01-25 |
TLR5 |
||||||
|
|
Human | 12.5% SDS-PAGE Stained with Coomassie Blue. | in vitro transl. | ||||
| Abnova Taiwan Corp. | |||||||
| H00007100-Q03-10 |
TLR5 |
||||||
|
|
Human | 12.5% SDS-PAGE Stained with Coomassie Blue | |||||
| Abnova Taiwan Corp. | |||||||
| H00007100-Q03-25 |
TLR5 |
||||||
|
|
Human | 12.5% SDS-PAGE Stained with Coomassie Blue | |||||
| Abnova Taiwan Corp. | |||||||
Positive controls for TLR5 (2 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| NBL1-16954 |
TLR5 Lysate |
||||||
![Western Blot: TLR5 Lysate [NBL1-16954] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for TLR5](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/TLR5%20Lysate-Western%20Blot-NBL1-16954-img0001.jpg) |
|||||||
| Novus Biologicals Inc. | |||||||
| LY401126 |
TLR5 overexpression lysate |
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|
0.1 mg /
€495.00
|
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| OriGene Technologies, Inc. | |||||||
Recommended Secondary Antibodies for TLR5 (11 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1253AP |
Mouse IgG (H+L chain) antibody |
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|
|
Rabbit | AP | C, E, WB | ||||
| Acris Antibodies GmbH | |||||||
| R1253B |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | Biotin | C, E, WB | ||||
| Acris Antibodies GmbH | |||||||
| R1253F |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | FITC | E, ICC/IF | ||||
| Acris Antibodies GmbH | |||||||
| R1253HRP |
Mouse IgG (H+L chain) antibody |
||||||
|
Rabbit | HRP | C, E, WB | ||||
| Acris Antibodies GmbH | |||||||
| R1253TR |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | Texas Red | ICC/IF | ||||
| Acris Antibodies GmbH | |||||||
| R1403R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Rabbit | PE | F | ||||
| Acris Antibodies GmbH | |||||||
| R1405R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Goat | PE | |||||
| Acris Antibodies GmbH | |||||||
| R1455R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
| R1457C2 |
Mouse IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy2 | |||||
| Acris Antibodies GmbH | |||||||
| R1457C3 |
Mouse IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy3 | |||||
| Acris Antibodies GmbH | |||||||
| R1457C5 |
Mouse IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy5 | |||||
| Acris Antibodies GmbH | |||||||
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