Product Description for ATM
Properties: pSer1981 Control Peptide
Properties for ATM
|Product Category||Control Peptides|
|Synonyms||A-T mutated, Ataxia telangiectasia mutated, Serine-protein kinase ATM|
|PDF datasheet||View Datasheet|
|Manufacturer||Acris Antibodies GmbH|
|Material safety datasheet||MSDS for Polyclonal Antibodies (de)|
|Property||pSer1981 Control Peptide|
|Add. information||Purity: > 95% specific peptide
Amino Acid Sequence: S-L-A-F-E-E-G-Sp-Q-S-T-T-I-S-S
|Application||Intended for use as a Control Peptide when used with anti-ATM (Cat#R1475P) to block specific interaction of anti-ATM with ATM.
The Control Peptide should be used at 1.0 µg per 1.0 µl of antiserum.
|Background||ATM is a 370 kDa nuclear phosphoprotein involved in the autosomal recessive disease Ataxia Telangiectasia (AT). ATM belongs to a novel family of proteins associated with cell cycle regulation, apoptosis, and response to DNA damage repair (DNA damage caused by such things as ionizing irradiation activates ATM kinase). The C terminal region has extensive homology to the catalytic domains of Phosphatidylinositol 3 kinases (PI3 kinases).|
|Concentration||1.0 mg/ml (by weight)|
|Storage||Store vial at -20°C or below prior to opening.
For extended storage aliquot contents and freeze at -20°C or below.
Dilute only prior to immediate use.
Avoid cycles of freezing and thawing.
Shelf life: One year from despatch.
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