discontinued

GTX25216 Cortactin Phospho + Non-Phospho control peptides

Search for all "Cortactin"

1 packs / €450.00

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anti Cortactin

GTX25216

Product Description for Cortactin

anti Cortactin.
Properties: Phospho + Non-Phospho control peptides

Properties for Cortactin

Product Category Control Peptides
Quantity 1 packs
Clonality Polyclonal
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Property Phospho + Non-Phospho control peptides
Background Cortactin is an 80/85 kDa cytoskeleton protein that facilitates assembly of cortical actin. Cortactin is widely expressed in most adherent cells and is a prominent substrate of protein-tyrosine kinase Src in vivo and in vitro. The protein sequence of cortactin contains multiple amino-terminal tandem repeats of a unique 37-amino acid sequence, which associates with actin, and a Src homology 3 (SH3) domain at the carboxyl terminus. Between the repeat and the SH3 domain, there is an alpha-helical structure followed by a proline-rich region. Between the proline-rich region and the SH3 domain, there are a series of Src phosphorylation sites (Tyr 421, Tyr 470, and Tyr 486). In vitro, cortactin binds to and cross-links F-actin into meshworks.
Format
Buffer System:
Lyophilized powder with trifluoroacetate salt.

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