Antibodies to Epithelial Cell Adhesion Molecule (EpCAM) - FocusOn 125

Antibody Panel to Epithelial Cell Surface Antigen EpCAM

Acris Antibodies offers a full range of thoroughly evaluated antibodies for specific detection of EpCAM using Western blotting and immunohistochemistry methods, and also other immunological applications, such as immunocytochemistry and immunoprecipitation (see Product list).

Introduction

Epithelial cell adhesion molecule (EpCAM) is a 40kD cell surface antigen. This antigen has been identified independently by a number of groups, and has been known by a variety of names: CD326, KSA, ESA, Lymphocyte antigen 74, M1S2, M4S1, GA733 2, MIC18, MK1, TACSTD1, TROP1.

Several monoclonal antibodies have been raised against EpCAM, many of which have been described as tumour specific molecules on carcinomas. EpCAM is a type 1 transmembrane glycoprotein. It is expressed on the basolateral membrane of cells by the majority of epithelial tissues, with the exception of adult squamous epithelium and some specific epithelial cell types including hepatocytes and gastric epithelial cells.

EpCAM expression has been reported to be a possible marker of early malignancy, with expression being increased in tumour cells, and de novo expression being seen in dysplastic squamous epithelium. It is intricately linked with the cadherin-catenin pathway and hence the fundamental Wnt pathway responsible for intracellular signalling and polarity. It has been used as an immunotherapeutic target in the treatment of gastrointestinal, urological and other carcinomas. It is expressed in undifferentiated pluripotent stem cells.

Fig. 1: Cell membrane staining of tumor cells (formalin-fixed, paraffin-embedded [FFPE] human breast carcinoma) using EpCAM antibody clone AUA1 Cat.-No. AM00557PU-N and peroxidase-conjugate/DAB chromogen
Fig. 1: Cell membrane staining of tumor cells (formalin-fixed, paraffin-embedded [FFPE] human breast carcinoma) using EpCAM antibody clone AUA1 Cat.-No. AM00557PU-N and peroxidase-conjugate/DAB chromogen
Fig. 2: Western blot analysis of rat colon probed with EpCAM antibody Cat.-No. AM32818SU-S (Clone GZ-1).
Fig. 2: Western blot analysis of rat colon probed with EpCAM antibody Cat.-No. AM32818SU-S (Clone GZ-1).
Fig. 3: Human breast carcinoma (FFPE) stained with EpCAM antibody clone SPM491 Cat.-No. AM11133PU-S
Fig. 3: Human breast carcinoma (FFPE) stained with EpCAM antibody clone SPM491 Cat.-No. AM11133PU-S
Fig. 4: Human colon carcinoma tissue (FFPE) stained with EpCAM antibody clone MOC-31 Cat.-No. DM2014S
Fig. 4: Human colon carcinoma tissue (FFPE) stained with EpCAM antibody clone MOC-31 Cat.-No. DM2014S
Fig. 5: Cell membrane staining of tumor cells (human breast carcinoma [FFPE]) with EpCAM antibody clone Ber-EP4 Cat.-No. DM406-05 using peroxidase-conjugate and AEC chromogen
Fig. 5: Cell membrane staining of tumor cells (human breast carcinoma [FFPE]) with EpCAM antibody clone Ber-EP4 Cat.-No. DM406-05 using peroxidase-conjugate and AEC chromogen
 

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD326 / EPCAM / TACSTD1 antibody

CD326 / EPCAM / TACSTD1 Mouse IgG1 HEA125 FITC Hu C, ICC/IF, P
0.25 ml / €410.00
  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

CD326 / EPCAM / TACSTD1 Mouse IgG1 ESA214 Purified Hu C, F, ICC/IF, P

Regular Price: 1 ml / €360.00

Special Price: 1 ml / €175.00

  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

CD326 / EPCAM / TACSTD1 Mouse IgG1 ESA214 Purified Hu C, F, ICC/IF, P
0.5 ml / €270.00
  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

AM11133PU clone SPM491 Ep-CAM Antibody Staining of Formalin-Fixed, Paraffin-Embedded Human breast carcinoma. Mouse IgG1 SPM491 Purified Hu P
1 ml / €500.00
  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

AM11133PU clone SPM491 Ep-CAM Antibody Staining of Formalin-Fixed, Paraffin-Embedded Human breast carcinoma. Mouse IgG1 SPM491 Purified Hu P
0.1 ml / €190.00
  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

Western blot analysis of Rat colon probed with EpCAM Antibody (Clone GZ-1). Mouse IgG1 GZ-1 Supernatant Rt C, F, ICC/IF, IP, P, WB
1.0 ml / €360.00
  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

Western blot analysis of Rat colon probed with EpCAM Antibody (Clone GZ-1). Mouse IgG1 GZ-1 Supernatant Rt C, F, ICC/IF, IP, P, WB
0.5 ml / €290.00
  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

Western blot analysis of Rat colon probed with EpCAM Antibody (Clone GZ-1). Mouse IgG1 GZ-1 Supernatant Rt C, F, ICC/IF, IP, P, WB
0.1 ml / €150.00
  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

Western blot analysis of Rat colon probed with EpCAM Antibody (Clone GZ-20). Mouse IgG1 GZ-20 Supernatant Rt C, F, ICC/IF, IP, P, WB
1.0 ml / €360.00
  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

Western blot analysis of Rat colon probed with EpCAM Antibody (Clone GZ-20). Mouse IgG1 GZ-20 Supernatant Rt C, F, ICC/IF, IP, P, WB
0.5 ml / €290.00
  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

Western blot analysis of Rat colon probed with EpCAM Antibody (Clone GZ-20). Mouse IgG1 GZ-20 Supernatant Rt C, F, ICC/IF, IP, P, WB
0.1 ml / €150.00
  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

CD326 / EPCAM / TACSTD1 Mouse IgG1 ESA214 FITC Hu C, F, ICC/IF
0.2 mg / €390.00
  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

CD326 / EPCAM / TACSTD1 Mouse IgG1 ESA214 FITC Hu C, F, ICC/IF
0.1 mg / €300.00
  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

CD326 / EPCAM / TACSTD1 Mouse IgG1 HEA125 Purified Hu C, ICC/IF, P, WB
50 µg / €300.00
  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

CD326 / EPCAM / TACSTD1 Mouse IgG1 HEA125 Purified Hu C, F, ICC/IF, P
0.1 mg / €950.00
  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

CD326 / EPCAM / TACSTD1 Mouse IgG1 HEA125 Purified Hu C, ICC/IF, P, WB
5 ml / €220.00
  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

DM406 clone Ber-EP4 Ep-CAM Antibody Staining of Formalin-Fixed, Paraffin-Embedded Human breast carcinoma using peroxidase-conjugate and AEC chromogen. Note cell membrane staining of tumor cells. Mouse IgG1 Ber-EP4 Supernatant Hu P
1 ml / €510.00
  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

DM406 clone Ber-EP4 Ep-CAM Antibody Staining of Formalin-Fixed, Paraffin-Embedded Human breast carcinoma using peroxidase-conjugate and AEC chromogen. Note cell membrane staining of tumor cells. Mouse IgG1 Ber-EP4 Supernatant Hu P
0.5 ml / €340.00
  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

CD326 / EPCAM / TACSTD1 Mouse IgG1 MOC-31 Azide Free Hu C, F, P
1 mg / €1,130.00
  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

CD326 / EPCAM / TACSTD1 Mouse IgG1 MOC-31 Purified Hu, Ms C, F, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

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