Antibodies to Prolactin Receptor - FocusOn 048

Introduction: Prolactin (PRL) is a hormone involved in a variety of important functions including ion transport and osmoregulation, stimulation of milk, protein synthesis as well as the regulation of numerous reproductive functions.

PRL exerts its influence on different cell types through a signal transduction pathway which begins with the binding of the hormone to a transmembrane PRL receptor. Immunoreactive PRL receptor, a member of the cytokine receptor family, varies in size (short and long forms) with tissue source and species, from ~40 kDa to 100 kDa. The PRL receptor consists of at least three separate domains: an extracellular region with 5 cysteines which contains the prolactin binding site, a single transmembrane domain and a cytoplasmic region, the length of which appears to influence ligand binding and regulate cellular function.

Tools for the Detection of Prolactin Receptor

Acris Antibodies offers a panel of antibodies to PRL receptor, suitable for immunological detection methods like immunohistochemistry, immunofluorescence microscopy or Western blotting. Recombinant Prolactin receptor is also available.



Fig. 1 illustrates immunohistochemical staining of PRL receptor in rat Islets of Langerhans using antibody SM5033P.

Fig. 1 illustrates immunohistochemical staining of PRL receptor in rat Islets of Langerhans using antibody SM5033P.

Fig. 2 illustrates immunohistochemical staining of PRL receptor in NB2 cells using antibody SM5034P.

Fig. 2 illustrates immunohistochemical staining of PRL receptor in NB2 cells using antibody SM5034P.

Available antibody panel to Prolactin Receptor

Prolactin receptor (PRL receptor, PRLR) antibody

6 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Prolactin receptor antibody

Prolactin receptor Mouse IgG1 SPM213 Purified Hu C, F, ICC/IF, IP, P, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

Prolactin receptor antibody

Prolactin receptor Mouse IgG1 SPM213 Purified Hu C, F, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Prolactin receptor antibody

Prolactin receptor Mouse IgG1 SPM213 Purified Hu C, F, ICC/IF, IP, P, WB
20 µg / €160.00
  Acris Antibodies GmbH

Prolactin receptor (25-29) antibody

Western blot analysis of extracts from 293T cells expressing human PRLR protein using PRLR Antibody AP26068PU-N. Rabbit Aff - Purified Hu WB
0.1 ml / €270.00
  Acris Antibodies GmbH

Prolactin receptor (25-29) antibody

Western blot analysis of extracts from 293T cells expressing human PRLR protein using PRLR Antibody AP26068PU-N. Rabbit Aff - Purified Hu WB
50 µl / €230.00
  Acris Antibodies GmbH

Prolactin receptor antibody

Prolactin receptor Sheep Purified Hu, Ms, Rt E, WB
1 ml / €300.00
  Acris Antibodies GmbH

6 Item(s)

per page
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