Antibody Panel to Transcription Factor AP-2 - FocusOn 064

Introduction

AP-2 is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes.

AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and c-Myc. There are three isoforms of AP-2: AP-2 alpha, beta and gamma. AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. It binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members. AP-2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.

Antibody Tools for the Detection of AP-2

Acris Antibodies offers a panel of antibodies to AP-2 (alpha, beta, gamma). These antibodies are suitable for immunological detection methods like immunohistochemistry or Western blotting / ELISA. A range of AP-2 antigens is also available.

Staining of human breast carcinoma using monoclonal antibody to AP-2 code DM333Western blot analysis of human MCS-7 cells using polyclonal antibody to AP-2 code SP7011P

Fig. 1: Staining of human breast carcinoma using AP-2 antibody DM333

Fig. 2: Western blot analysis of human MCS-7 cells using AP-2 antibody SP7011P

Available Antibody Panel to AP-2

Transcription factor AP-2, AP-2 alpha, AP-2 beta, AP-2 gamma ( TFAP2A, TFAP2B, TFAP2C [ERF-1] ) antibody

14 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

AP-2 beta / TFAP2B antibody

Transfected 293T; WB Suggested Anti-TFAP2B Antibody. . Titration: 2.5 ug/ml. . Positive Control: Transfected 293T; TFAP2B antibody - C-terminal region (ARP33432_T100) in Transfected 293T cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Por, Rt, Ze WB
0.1 mg / €310.00
  AVIVA Systems Biology

AP-2 beta / TFAP2B antibody

Transfected 293T; WB Suggested Anti-TFAP2B Antibody Titration: 0.2-1 ug/ml. Positive Control: Transfected 293T; TFAP2B antibody - N-terminal region (ARP38282_P050) in Transfected 293T cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

AP-2 beta / TFAP2B antibody

Transfected 293T; WB Suggested Anti-TFAP2B Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Transfected 293T; TFAP2B antibody - N-terminal region (ARP57907_P050) in Transfected 293T cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

AP-2 beta / TFAP2B antibody

AP-2 beta / TFAP2B Mouse IgG2b AP2b 1G6/2 Purified Hu E, WB
0.1 mg / €320.00
  Novus Biologicals Inc.

TFAP2A / AP-2 alpha antibody

Immunohistochemical analysis in paraffin-embedded human lung carcinoma tissue using TFAP2A / AP-2 alpha antibody (Cat.-No. AP06013PU-N). Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

TFAP2A / AP-2 alpha (3-14) antibody

AP07641PU-N TFAP2A antibody staining of Formalin-Fixed Paraffin-Embedded Human Kidney at 2.5 µg/ml followed by biotinylated anti-Goat IgG secondary antibody, Alkaline Phosphatase-Streptavidin and Chromogen. Goat Aff - Purified Can, Chk, Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

TFAP2A / AP-2 alpha (C-term) antibody

Western blot analysis of TFAP2A Antibody (C-term) (AP11820PU-N) in NCI-H460 cell line lysates (35 µg/lane). TFAP2A (arrow) was detected using the purified Pab (1:60 dilution). Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TFAP2A / AP-2 alpha antibody

Human HepG2; WB Suggested Anti-TFAP2A Antibody Titration: 1.25ug/ml. ELISA Titer: 1:312500. Positive Control: HepG2 cell lysate; TFAP2A antibody - C-terminal region (P100878_T100) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Bov, Chk, Hu, Ms, Por, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

TFAP2A / AP-2 alpha antibody

TFAP2A / AP-2 alpha Rabbit Aff - Purified Hu, Ms, Rt IP, P, WB
0.1 ml / €420.00
  Neuromics Antibodies

TFAP2A / AP-2 alpha antibody

TFAP2A / AP-2 alpha Mouse IgG1 AP2a 8G8/5 Purified Hu P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

TFAP2A / AP-2 alpha antibody

Immunohistochemistry: AP-2 Antibody (A6/2/2) [NB100-64815] - Human Breast Epithelium stained with Mouse anti Human AP-2 Mouse IgG 30037 Aff - Purified Hu C, E, P, WB
0.1 mg / €510.00
  Novus Biologicals Inc.

TFAP2A / AP-2 alpha antibody

Western Blot: AP-2 Antibody (3B5) [NB100-74359] - Figure 1 illustrates Western blot detection of AP-2 from MCF7 cell lysate. Mouse IgG2b 3B5 Purified Chk, Hu, Ms ICC/IF, IP, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

TFAP2A / AP-2 alpha/beta antibody

TFAP2A / AP-2 alpha/beta Mouse IgG1 A6/2/2 Purified Hu E, F, P, R, WB
0.1 mg / €340.00
  Novus Biologicals Inc.

TFAP2D antibody

Human Muscle; WB Suggested Anti-TFAP2D Antibody Titration: 2.5ug/ml. ELISA Titer: 1:312500. Positive Control: Human Muscle; TFAP2D antibody - C-terminal region (ARP30084_T100) in Human Muscle cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt, Ze WB
0.1 mg / €310.00
  AVIVA Systems Biology

14 Item(s)

per page
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