EA101016 17-a-OHP CLIA Kit

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1 kit / €280.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

EA101016

Properties for 17-a-OHP CLIA Kit

Product Category ELISA Kits
Quantity 1 kit
Synonyms 17-OHP
Reactivity Hu
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Add. information
Interference:
No significant interference observed with available related molecules.
Application
Specificity:
Natural and recombinant human 17a Hydroxy Progesterone
Assay Type:
Chemiluminescence Immunoassay (CLIA)
Signal:
Colorimetric
Sample Type:
Cell culture supernatant, serum, plasma
Sample Volume:
20 ul
Curve Range:
0.05 – 20 ng/mL
Background The steroid 17-a-Hydroxyprogesterone (17-a-OHP) is produced by both the adrenal cortex and gonads. Even though 17-a-OHP has relatively little progestational activity, it is of intense clinical interest because it is the immediate precursor to 11-desoxycortisol (Cpd-S). Because Cpd-S is produced by 21-hydroxylation of 17-a-OHP, measurement of 17-a-OHP is a useful indirect indicator of 21-hydroxylase activity. In congenital 21-hydroxylase deficiency, the most common variety of congenital adrenal hyperplasia (CAH), 17-a-OHP is secreted in abundant excess. It is moderately elevated in the 11-ß-hydroxylase deficiency as well. Measurement of 17-a-OHP is therefore valuable in the initial diagnosis of CAH.
Assaytime 3 hours
Range 0.05 ng/ml
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