BB-EK0777 Human IL-6R alpha ELISA Kit

Search for all "Human IL-6R alpha ELISA Kit"

96 Tests / €460.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

BB-EK0777

Properties for Human IL-6R alpha ELISA Kit

Product Category ELISA Kits
Quantity 96 Tests
Reactivity Hu
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Boster Immunoleader
Manufacturer certificates ISO 9001

Datasheet Extract

Immunogen
Swiss Prot Num:
A0N0L5
Add. information Sensitivity < 10 pg/ml
Application Sandwich ELISA kit of Quantitative Detection for Human IL-6R alpha
This kit is used for quantitative detection of human IL-6R Alpha in cell culture supernates, serum, plasma(heparin, EDTA, citrate) and urine.
There is no detectable cross-reactivity with other relevant proteins.
Background IL6R alpha(IL6RA) also known as CD126 or IL6R, is a type I cytokine receptor. The IL6 receptor is a protein complex consisting of a IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer Glycoprotein 130. IL6R also denotes the human gene encoding this subunit. Alternatively spliced transcript variants encoding distinct isoforms have been reported. IL6R subunit is also shared by many other cytokines. Interleukin-6 receptor has been shown to interact with Interleukin 6 and Ciliary neurotrophic factor. Ligand binding did not appear to affect IL6R dimerization status. IL6R dimerization occurs both on the cell surface and in solution.
General Readings
  1. Hoek KS, Schlegel NC, Eichhoff OM, Widmer DS, Praetorius C, Einarsson SO, et al. Novel MITF targets identified using a two-step DNA microarray strategy. Pigment Cell Melanoma Res. 2008 Dec;21(6):665-76. doi: 10.1111/j.1755-148X.2008.00505.x. PubMed PMID: 19067971.
  2. "Entrez Gene: IL6R interleukin 6 receptor"
  3. Taga T, Hibi M, Hirata Y, Yamasaki K, Yasukawa K, Matsuda T, et al. Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130. Cell. 1989 Aug 11;58(3):573-81. PubMed PMID: 2788034.
  4. Schuster B, Meinert W, Rose-John S, Kallen KJ. The human interleukin-6 (IL-6) receptor exists as a preformed dimer in the plasma membrane. FEBS Lett. 2003 Mar 13;538(1-3):113-6. PubMed PMID: 12633863.
Storage Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
Range 31.2-2000 pg/ml
  • LinkedIn