BB-EK0458 Human MMP-1 ELISA Kit

Search for all "Human MMP-1 ELISA Kit"

96 Tests / €470.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

BB-EK0458

Properties for Human MMP-1 ELISA Kit

Product Category ELISA Kits
Quantity 96 Tests
Reactivity Hu
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Boster Immunoleader
Manufacturer certificates ISO 9001

Datasheet Extract

Immunogen
Swiss Prot Num:
B4DN15
Add. information Sensitivity < 20 pg/ml
Application Sandwich ELISA kit of Quantitative Detection for Human MMP-1
This kit is used for quantitative detection of human MMP-1 in cell culture supernates, serum and plasma(heparin, EDTA).
There is no detectable cross-reactivity with other relevant proteins.
Background Matrix metalloproteinase-1 (MMP-1) is also known as collagenase. Matrix metalloproteinases (MMPs) are zinc-dependent proteases that degrade extrMMP-1llular matrix proteins. The MMPs comprise a family of at least 20 proteolytic enzymes that play an essential role in tissue remodeling. Matrix metalloproteinase-1 (MMP-1) plays an important role in the degradation of collagen in inflammatory diseases.1 MMP1 (interstitial collagenase), MMP9 (gelatinase B) and MMP12 (macrophage elastase) are thought to be important in the development of emphysema.2 Smoking-induced MMP-1 might be important in the skin-ageing effects of tobacco smoking.3 The standard product used in this kit is human MMP-1 with the molecular mass of 51-53KDa. The detected MMP-1 includes zymogen and active enzyme.
General Readings
  1. Domeij H, Modéer T, Quezada HC, Yucel-Lindberg T. Cell expression of MMP-1 and TIMP-1 in co-cultures of human gingival fibroblasts and monocytes: the involvement of ICAM-1. Biochem Biophys Res Commun. 2005 Dec 30;338(4):1825-33. Epub 2005 Nov 2. PubMed PMID: 16288711.
  2. Joos L, He JQ, Shepherdson MB, Connett JE, Anthonisen NR, Paré PD, et al. The role of matrix metalloproteinase polymorphisms in the rate of decline in lung function. Hum Mol Genet. 2002 Mar 1;11(5):569-76. PubMed PMID: 11875051.
  3. Lahmann C, Bergemann J, Harrison G, Young AR. Matrix metalloproteinase-1 and skin ageing in smokers. Lancet. 2001 Mar 24;357(9260):935-6. PubMed PMID: 11289356.
Storage Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
Range 156-10,000 pg/ml
  • LinkedIn