BB-EK0832 Mouse RBP4 ELISA Kit

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Properties for Mouse RBP4 ELISA Kit

Product Category ELISA Kits
Quantity 96 Tests
Reactivity Ms
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Boster Immunoleader
Manufacturer certificates ISO 9001

Datasheet Extract

Swiss Prot Num:
Add. information Sensitivity < 10 pg/ml
Application Sandwich ELISA kit of Quantitative Detection for Mouse RBP4
This kit is used for quantitative detection of mouse RBP4 in cell culture supernates, serum, plasma(heparin , EDTA) and urine.
There is no detectable cross-reactivity with other relevant proteins.
Background Retinol binding protein 4, plasma, also known as RBP4, belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It is protein that it is encoded by the RBP4 gene. RBP4 gene resides just centromeric of the cluster of CYP2C genes on 10q24. The mouse Rbp4 locus is closely linked and just proximal to the locus for phenobarbital-inducible cytochrome P450-2c (Cyp-2c) at the distal end of chromosome 19. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. The standard product used in this kit are recombinant mouse B7-1/CD80, D37—K245, consisting of dimer acids with two single straned. The standard used in this kit is recombinant protein, with E19-L201 aa sequence, the molecular weight is 22kda.
General Readings
  1. Rask L, Anundi H, Fohlman J, Peterson PA. The complete amino acid sequence of human serum retinol-binding protein. Ups J Med Sci. 1987;92(2):115-46. PubMed PMID: 2444024.
  2. Rocchi M, Covone A, Romeo G, Faraonio R, Colantuoni V. Regional mapping of RBP4 to 10q23----q24 and RBP1 to 3q21----q22 in man. Somat Cell Mol Genet. 1989 Mar;15(2):185-90. PubMed PMID: 2928844.
  3. "Entrez Gene: RBP4 retinol binding protein 4, plasma". M., Covone, A., Romeo, G., Faraonio, R., Colantuoni, V. Regional mapping of RBP4 to 10q23-q24 and RBP1 to 3q21-q22 in man. Somat. Cell Molec. Genet. 15: 185-190, 1989.
Storage Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
Range 312-20,000 pg/ml
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