BB-EK0712 Rat CD86/ B7-2 ELISA Kit

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96 Tests / €460.00
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Properties for Rat CD86/ B7-2 ELISA Kit

Product Category ELISA Kits
Quantity 96 Tests
Reactivity Rt
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Boster Immunoleader
Manufacturer certificates ISO 9001

Datasheet Extract

Swiss Prot Num:
Add. information Sensitivity < 10 pg/ml
Application Sandwich ELISA kit of Quantitative Detection for Rat CD86/ B7-2
This kit is used for quantitative detection of rat CD86 in cell culture supernates and serum.
There is no detectable cross-reactivity with other relevant proteins.
Background Cluster of Differentiation 86 (also known as CD86 and B7-2) is aprotein expressed on antigen-presenting cells that provides costimulatory signals necessary for T cell activation and survival. The CD86 gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. Using fluorescence in situ hybridization mapping, the CD86, like CD80, was mapped to human 3q21 and mouse chromosome 16, band B5. The antigen presentation coactivators B71 and B72, which are important in other immune-mediated thyroid diseases, are important for lymphocytic infiltration and the immune response against thyroid carcinoma.
General Readings
  1. Chen C, Gault A, Shen L, Nabavi N. Molecular cloning and expression of early T cell costimulatory molecule-1 and its characterization as B7-2 molecule. J Immunol. 1994 May 15;152(10):4929-36. PubMed PMID: 7513726.
  2. Reeves RH, Patch D, Sharpe AH, Borriello F, Freeman GJ, Edelhoff S, et al. The costimulatory genes Cd80 and Cd86 are linked on mouse chromosome 16 and human chromosome 3. Mamm Genome. 1997 Aug;8(8):581-2. PubMed PMID: 9250865.
  3. Shah R, Banks K, Patel A, Dogra S, Terrell R, Powers PA, et al. Intense expression of the b7-2 antigen presentation coactivator is an unfavorable prognostic indicator for differentiated thyroid carcinoma of children and adolescents. J Clin Endocrinol Metab. 2002 Sep;87(9):4391-7. PubMed PMID: 12213904.
Storage Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
Range 62.5-4000 pg/ml
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