2-1501-001 Strep-Tactin(R) Coated Microplate Kit

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  • 2-1501-001

Properties for Strep-Tactin(R) Coated Microplate Kit

Product Category ELISA Kits
Quantity 1 Plates
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract


Apoptosis, a form of programmed cell death in multicellular organisms, is directly triggered by FasL(igand)/Fas system. FasL also known as CD95L plays a pivotal role in regulating normal B and T cell function, suppression of autoimmunity, control of infection, and immune surveillance. As a result of its dual role, namely, in self-control of T cell expansion and in killing of virally infected or neoplastically transformed target cells, Fas/FasL system is involved in disease areas such as autoimmune diseases, cancer and immune deficiency, which are all well-known features of neoplastic diseases, in particular, of the lympho-hematopoietic system.

FasL binds the Fas receptor (also known as Apo-1 or CD95), a transmembrane protein, which is part of the TNFR superfamily. The interaction between Fas receptor and FasL results in the formation of the death-inducing signaling complex (DISC), which contains FADD, caspase-8 and caspase-10. In many cell types, processed pro-caspase-8 directly activates other members of the caspase family, and triggers the execution of apoptosis.

Storage Store at 4C. Do not freeze.
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