discontinued

NBL1-13790 NRG1 Lysate

Search for all "NRG1 Lysate"

Product Description for NRG1 Lysate

Product is tested for Western blot / Immunoblot.

Properties for NRG1 Lysate

Product Category Lysates
Target Category
Quantity 0.1 mg
Synonyms ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, NDF, SMDF
Applications WB
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q02297
Add. information This product is manufactured by and sold under license from OriGene Technologies and its use is limited solely for research purposes.
Research Areas: Neuroscience
Application Western Blot, This product is intended for use as a positive control in Western Blot., Western Blot
Background Neuregulin 1 (NRG1) was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. It is known that an extraordinary variety of different isoforms are produced from the NRG1 gene by alternative splicing. These isoforms include heregulins (HRGs), glial growth factors (GGFs) and sensory and motor neuron-derived factor (SMDF). They are tissue-specifically expressed and differ significantly in their structure. The HRG isoforms all contain immunoglobulin (Ig) and epidermal growth factor-like (EGF-like) domains. GGF and GGF2 isoforms contain a kringle-like sequence plus Ig and EGF-like domains; and the SMDF isoform shares only the EGF-like domain with other isoforms. The receptors for all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. Through interaction with ERBB receptors, NRG1 isoforms induce the growth and differentialtion of epithelial, neuronal, glial, and other types of cells. [provided by RefSeq]. Transcript Variant: This variant (HRG-beta1), along with HRG-alpha, beta2, and beta3 variants, was identified in various normal tissues and cancer cell lines. The protein product encoded by this variant is distinct from that of HRG-alpha in the region of amino acids 213-239. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Concentration 1 mg/ml
Storage Store at -20C. Avoid freeze-thaw cycles.
  • LinkedIn