NB110-81562 17-DMAG

Search for all "17-DMAG"

1 mg / €360.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.


Properties for 17-DMAG

Product Category Natural Compounds
Quantity 1 mg
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Add. information Synthetic 17-DMAG
Soluble in DMSO (>25mg/mL) and ethanol (10mg/mL)
Purple solid
Application , Synthetic 17-DMAG Soluble in DMSO (>25mg/mL) and ethanol (10mg/mL) Purple solid
Background 17-DMAG is a water soluble & cell-permeable analog of Geldanamycin and 17-AAG (1). It binds to the APTase site of human Hsp90a with high affinity, has cytotoxic activity against many cancer cell lines (2), and acts as angiogenesis inhibitor (3). This Hsp90 inhibitor shows promise in preclinical models. 17-DMAG has excellent bioavailability, is widely distributed to tissues, and is quantitatively metabolized much less than is 17-AAG.
General Readings
  1. Bull E.E., et al.(2004) Clin. Cancer Res. 10:8077.
  2. Gossett D.R. et al.(2005) Gynecol. Oncol. 96:381.
  3. Kaur G. et al.(2004) Clin. Cancer Res. 10:4813.
Storage Store at -20C. Avoid freeze-thaw cycles.
17-DMAG Compound
Not tested in other species.

Accessory Products

  • LinkedIn