AR09121PU-N Alpha-1-antitrypsin (25-418)

Search for all "Alpha-1-antitrypsin"

0.1 mg / €310.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Alpha-1-antitrypsin

AR09121PU-N

More Views

  • AR09121PU-N

Product Description for Alpha-1-antitrypsin

Alpha-1-antitrypsin.
Presentation: Purified

Properties for Alpha-1-antitrypsin

Product Category Proteins & Growth Factors
Target Category
Quantity 0.1 mg
Synonyms AAT, Alpha-1 protease inhibitor, Alpha-1-antiproteinase, SERPINA1
Presentation Purified
Molecular weight 44.4 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P01009
Purity > 90 % by SDS PAGE
Background Alpha 1 proteinase inhibitor (Antitrypsin) has a characteristic secondary structure of beta sheets and alpha helices. That is a serum glycoprotein synthesized in the liver. It acts as an elastase inhibitor, primarily inhibiting neutrophil elastase, chymotrypsin, collagenase, leucocytic proteases, plasmin, and thrombin, which may be released during inflammatory reactions in the lung. Also Increase in Antitrypsin occurs as an acute phase response to tissue necrosis and inflammation. Serum level of Antitrypsin is elevated in rheumatoid arthritis, bacterial infections, vasculitis, and carcinomatosis.
Concentration 1.0 mg/ml (determined by Bradford assay)
General Readings
  1. Kolarich D., et al. (2006), Proteomics 6(11):3369-80.
  2. Wu Y., et al. (1991), Bioessays. 13(4):163-9
Storage Store at 2-8°C for 1-2 weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant Antitrypsin protein was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MEDPQGDAAQ KTDTSHHDQD HPTFNKITPN LAEFAFSLYR QLAHQSNSTN IFFSPVSIAT AFAMLSLGTK ADTHDEILEG LNFNLTEIPE AQIHEGFQEL LRTLNQPDSQ LQLTTGNGLF LSEGLKLVDK FLEDVKKLYH SEAFTVNFGD TEEAKKQIND YVEKGTQGKI VDLVKELDRD TVFALVNYIF FKGKWERPFE VKDTEEEDFH VDQVTTVKVP MMKRLGMFNI QHCKKLSSWV LLMKYLGNAT AIFFLPDEGK LQHLENELTH DIITKFLENE DRRSASLHLP KLSITGTYDL KSVLGQLGIT KVFSNGADLS GVTEEAPLKL SKAVHKAVLT IDEKGTEAAG AMFLEAIPMS IPPEVKFNKP FVFLMIDQNT KSPLFMGKVV NPTQK
Molecular weight:
(395 aa), confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris pH 7.5, 10% Glycerol, 1 mM DTT, 2 mM EDTA
Purity:
>90% by SDS PAGE
State:
Liquid purified protein
Purified
  • LinkedIn