AR03037PU-L Alpha-crystallin A chain / CRYA1 (1-175)

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0.5 mg / €820.00
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Alpha-crystallin A chain / CRYA1

AR03037PU-L

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  • AR03037PU-L

Product Description for Alpha-crystallin A chain / CRYA1

Alpha-crystallin A chain / CRYA1.
Presentation: Purified

Properties for Alpha-crystallin A chain / CRYA1

Product Category Proteins & Growth Factors
Target Category
Quantity 0.5 mg
Synonyms CRYAA, HSPB4, Heat shock protein beta-4
Presentation Purified
Molecular weight 20 kDa
Source E. coli
Species (Protein) Mouse
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P24622
Purity > 95 % > 95 % by SDS PAGE
Add. information NCBI Accession No: NP_034094
Background Alpha crystallins are composed of two gene products, alpha-A and alpha-B for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20). They act as molecular chaperones and hold them in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of α-crystallins are an autokinase activity and participation in the intracellular architecture. CRYAB is expressed widely in many tissues and organs. Recombinant CRYAB was expressed in E.coli and purified by using conventional chromatography techniques.
Concentration 1.0 mg/ml
General Readings
  1. Hasan, A., et al.(2002) Biochemistry 41(52) 15876-15882 2. Kamradt,M.C., et al.(2002) J. Biol.Chem. 277(41) 38731-387363.
  2. Reddy, G.B., et al. (2002) FEBS lett. 522(1-3) 59-64
  3. Ito, H., et al. (2002) J.Biochem.131(4) 593-603
Storage Store (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Source E. coli
Description
Description:
Recombinant mouse Crystallin alpha A / CRYAA
AA Sequence:
MDIAIHHPWI RRPFFPFHSP SRLFDQFFGE HLLESDLFST ATSLSPFYLR PPSFLRAPSW IDTGLSEMRL EKDRFSVNLD VKHFSPEELK VKVLGDVIEV HGKHEERQDE HGFISREFHR KYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSGPERTIP ITREEKPAVA AAPKK
Molecular weight:
20 kDa (175 aa)
Format
Buffer System:
20mM Tris pH 8.0 and 10 % glycerol
Purity:
>95% > 95 % by SDS PAGE
State:
Liquid
Purified
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