discontinued

NB810-61093 CaM Kinase II

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0.5 µg / €360.00

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CaM Kinase II

Product Description for CaM Kinase II

CaM Kinase II.

Properties for CaM Kinase II

Product Category Proteins & Growth Factors
Quantity 0.5 µg
Synonyms Cam Kinase II, Rat Brain
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Add. information Research Areas: Neuroscience
Background Ca2+/calmodulin-dependent protein kinase II (CaM Kinase II) is a multi-functional calcium and calmodulin-dependent protein kinase that mediates cellular responses to a wide variety of intercellular signals (Kennedy, 1998; Schulman and Hanson, 1993). CaM Kinase II has been shown to regulate diverse cellular functions including synaptic plasticity, neurotransmitter synthesis and release, gene expression, ion channel function, carbohydrate metabolism, cytoskeletal function, and Ca2+-homeostasis (Gleason et al., 2003; Soderling, 2000; Hudmon and Schulman, 2002).
Concentration 0.02 mg/ml
General Readings
  1. Gleason MR, Higashijima S, Dallman J, Liu K, Mandel G, Fetcho JR. Translocation of CaM kinase II to synaptic sites in vivo. Nat Neurosci. 2003 Mar;6(3):217-8. PubMed PMID: 12563265.
  2. Hudmon A, Schulman H. Neuronal CA2+/calmodulin-dependent protein kinase II: the role of structure and autoregulation in cellular function. Annu Rev Biochem. 2002;71:473-510. Epub 2001 Nov 9. PubMed PMID: 12045104.
  3. Kennedy MB. Signal transduction molecules at the glutamatergic postsynaptic membrane. Brain Res Brain Res Rev. 1998 May;26(2-3):243-57. PubMed PMID: 9651538.
  4. Schulman H, Hanson PI. Multifunctional Ca2+/calmodulin-dependent protein kinase. Neurochem Res. 1993 Jan;18(1):65-77. PubMed PMID: 8385278.
  5. Soderling TR. CaM-kinases: modulators of synaptic plasticity. Curr Opin Neurobiol. 2000 Jun;10(3):375-80. PubMed PMID: 10851169.
Storage Store at -80C. Avoid freeze-thaw cycles.
Format
Buffer System:
No Preservative
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