AR31160PU-N CD153 / CD30L

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50 µg / €330.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

CD153 / CD30L

AR31160PU-N

Product Description for CD153 / CD30L

CD153 / CD30L.
Presentation: Purified

Properties for CD153 / CD30L

Product Category Proteins & Growth Factors
Target Category
Quantity 50 µg
Synonyms CD30 Ligand, CD30-L, CD30LG, TNFSF8, Tumor necrosis factor ligand superfamily member 8
Presentation Purified
Reactivity Hu, Ms
Molecular weight 21.3 kDa
Source CHO cells
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P32971
Purity > 98 % by SDS-PAGE & HPLC analysis
Add. information Centrifuge vials before opening!
Background The type-II membrane-associated glycoprotein CD30 ligand (CD30L) is a protein belonging to the TNF superfamily. The CD30L gene encodes for a 234 amino acid type II transmembrane protein, which contains a 37 amino acid cytoplasmic sequence, a 25 amino acid transmembrane domain and a 172 amino acid extracellular domain. The protein is expressed primarily on certain B cells, T cells, and monocytes. CD30L binds specifically to CD30 (receptor), which is expressed on activated, but not resting, B and T cells, in lymphomas and various chronically inflamed tissues. CD30L/CD30 interactions initiate a signaling cascade that can ultimately lead to the activation of NF-KappaB. CD30L/CD30 signaling exerts pleiotropic effects on normal cells, including cell death, differentiation, or cell division. Certain diseases, including Hodgkins’s lymphoma, allergic inflammation, diabetes (in NOD mice), and mycobacterial infection can also be affected by CD30L/CD30 signaling.
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month 
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant Human soluble CD30L (sCD30L) is a 188 amino acid polypeptide corresponding to the extracellular domain, and contains an 8 residue N-terminal His-ag
AA Sequence:
HHHHHHHHPS PGGSGGQRTD SIPNSPDNVP LKGGNCSEDL LCILKR APFK KSWAYLQVAK HLNKTKLSWN KDGILHGVRY QDGNLVIQFP G LYFIICQLQ FLVQCPNNSV DLKLELLINK HIKKQALVTV CESGMQT KHV YQNLSQFLLD YLQVNTTISV NVDTFQYIDT STFPLENVLS IF LYSNSD
Biological activity:
Determined by its ability to stimulate human IL-8 production by human PBMC using a concentration range of 10.0-25.0 ng/ml. Note: Results may vary with PBMC donors.
Molecular weight:
(188 amino acids)
Format
Buffer System:
PBS without stabilizers
Purity:
>98% by SDS-PAGE & HPLC analysis
State:
Lyophilized purified protein
Purified
Reconstitution:
Restore in water to a concentration of 0.1-1.0 mg/ml.
This solution can be diluted into other aqueous buffers and stored at 4°C for one week or at –20°C for future use.
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