AR51469PU-N CD153 / CD30L (His-tag)

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0.5 mg / €730.00
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CD153 / CD30L

Product Description for CD153 / CD30L

CD153 / CD30L.
Presentation: Purified

Properties for CD153 / CD30L

Product Category Proteins & Growth Factors
Target Category
Quantity 0.5 mg
Synonyms CD30 Ligand, CD30-L, CD30LG, TNFSF8, Tumor necrosis factor ligand superfamily member 8
Presentation Purified
Molecular weight 22.0 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P32971
Purity > 80 % by SDS - PAGE
Background TNFSF8 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. TNFSF8 was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas.
Concentration 0.5 mg/ml (determined by Bradford assay)
General Readings Smith C.A., et al (1993). Armitage R.J. Cell 73:1349-1360Croager E.J., et al (1997). Biochim. Biophys. Acta 1353:231-235
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description
Description:
Recombinant human TNFSF8 protein, fused to His-tag at N-terminus, was expressed in E.coli.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSQRTDSIP NSPDNVPLKG GNCSEDLLCI LKRAPFKKSW AYLQVAKHLN KTKLSWNKDG ILHGVRYQDG NLVIQFPGLY FIICQLQFLV QCPNNSVDLK LELLINKHIK KQALVTVCES GMQTKHVYQN LSQFLLDYLQ VNTTISVNVD TFQYIDTSTF PLENVLSIFL YSNSD
Molecular weight:
(195aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea
Purity:
>80% by SDS - PAGE
State:
Liquid purified protein
Purified
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