AR50714PU-S CD178 / Fas Ligand (130-281, His-tag)

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0.1 mg / €300.00
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CD178 / Fas Ligand

Product Description for CD178 / Fas Ligand

CD178 / Fas Ligand.
Presentation: Purified

Properties for CD178 / Fas Ligand

Product Category Proteins & Growth Factors
Target Category
Quantity 0.1 mg
Synonyms APT1LG1, APTL, Apoptosis antigen ligand, CD95L protein, FASL, FASLG, Fas antigen ligand, TNFSF6, Tumor necrosis factor ligand superfamily member 6
Presentation Purified
Molecular weight 19.6 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P48023
Purity > 90 % by SDS - PAGE
Background Fas ligand, also known as FASLG, belongs to the tumor necrosis factor family and is the ligand for FAS. Both are transmembrane proteins. Interaction of FAS with this ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Defects in FASLG may be related to some cases of systemic lupus erythematosus (SLE).
Concentration 1 mg/ml (determined by Bradford assay)
General Readings
  • Kirkin V., et al. (2007) Cell Death Differ. 14:1678-1687.
  • Voss M., et al. (2009) BMC Immunol. 10:53-53.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human FASLG protein, fused to His-tag at N-terminus, was expressed in E.coli.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MQIGHPSPPP EKKELRKVAH LTGKSNSRSM PLEWEDTYGI VLLSGVKYKK GGLVINETGL YFVYSKVYFR GQSCNNLPLS HKVYMRNSKY PQDLVMMEGK MMSYCTTGQM WARSSYLGAV FNLTSADHLY VNVSELSLVN FEESQTFFGL YKL
Molecular weight:
(173aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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