discontinued

PA1111 CD4

Search for all "CD4"

Quick Overview

CD4

PA1111

Product Description for CD4

CD4.
Presentation: Purified

Properties for CD4

Product Category Proteins & Growth Factors
Target Category
Quantity 2 µg
Synonyms T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
Presentation Purified
Molecular weight 45 kDa
Source Insect cells
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P01730
Purity > 90 % pure as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Background CD4 is a cell-surface glycoprotein found on the mature helper T cells and immature thymocytes, as well as on monocytes and macrophages. (Some cytotoxic T cells have CD4 protein as well.) Normally, about 65% of T cells in the blood are CD4+ (have CD4 protein protruding from their membrane). A mature T cell with either have CD4 or CD8, but not both. During one stage of development T cells develop CD4 and CD8 receptors, but they eventually are differentiated in the thymus and become more specialized.
Concentration 10 µg / 38,7 µl
Storage Store the protein undiluted at 2-8°C for one week or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Shelf life: one year from despatch.
Source (Baculovirus)
Description
Description:
sCD4 Human Recombinant produced in Baculovirus is a single, glycosylated polypeptide chain containing 365 amino acids. As a result of glycosilation the sCD4 migrates as a 46 kDa protein on standard SDS-PAGE. Detected By Western Imunno Blots anti CD4 monoclonal antibody. The sCD4 is purified by proprietary chromatographic techniques.
AA Sequence:
KKVVL GKKGDTVELT CTASQKKSIQ FHWKNSNQIK ILGNQGSFLT KGPSKLNDRA DSRRSLWDQG NFPLIIKNLK IEDSDTYICE VEDQKEEVQL LVFGLTANSD THLLQGQSLT LTLESPPGSS PSVQCRSPRG KNIQGGKTLS VSQLELQDSG TWTCTVLQNQ KKVEFKIDIV VLAFQKASSI VYKKEGEQVE FSFPLAFTVE KLTGSGELWWQAERASSSKS WITFDLKNKE VSVKRVTQDP KLQMGKKLPL HLTLPQALPQ YAGSGNLTLALEAKTGKLHQ EVNLVVMRAT QLQKNLTCEV WGPTSPKLML SLKLENKEAK VSKREKAVWV LNPEAGMWQC LLSDSGQVLL ESNIKVLPTW
Biological activity:
Immune reactive in ELISA using monoclonal anti CD4 in gpl2O capture ELISA assays.
Molecular weight:
(non glycosilated Molecular Mass)
Format
Buffer System:
10 mM Sodium Phosphate buffer pH 7.0, 300 mM Sodium Chloride
Purity:
>90% pure as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
State:
Sterile filtered colorless solution.
Purified
  • LinkedIn