AR50701PU-S Complement factor D (26-253, His-tag)

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0.1 mg / €300.00
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Complement factor D

Product Description for Complement factor D

Complement factor D.
Presentation: Purified

Properties for Complement factor D

Product Category Proteins & Growth Factors
Target Category
Quantity 0.1 mg
Synonyms Adipsin, C3 convertase activator, CFD, DF, PFD, Properdin factor D
Presentation Purified
Molecular weight 26.6 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P00746
Purity > 85 % by SDS - PAGE
Background CFD, also known as adipsin, is involved in the alternative complement pathway of the complement system where it cleaves factor B. This protein is a member of the trypsin family of peptidases. It is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. It is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, it has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology.
Concentration 1 mg/ml (determined by Bradford assay)
General Readings Narayana SV. et al. (1994) J Mol Biol. 235:695-708.Ronti T. et al. (2006) Clin Endocrinol (Oxf). 64:355-365.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human CFD protein, fused to His-tag at N-terminus, was expressed in E.coli.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MILGGREAEA HARPYMASVQ LNGAHLCGGV LVAEQWVLSA AHCLEDAADG KVQVLLGAHS LSQPEPSKRL YDVLRAVPHP DSQPDTIDHD LLLLQLSEKA TLGPAVRPLP WQRVDRDVAP GTLCDVAGWG IVNHAGRRPD SLQHVLLPVL DRATCNRRTH HDGAITERLM CAESNRRDSC KGDSGGPLVC GGVLEGVVTS GSRVCGNRKK PGIYTRVASY AAWIDSVLA
Molecular weight:
(249aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea
Purity:
>85% by SDS - PAGE
State:
Liquid purified protein
Purified
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