AR51918PU-N Complement factor D (21-253, His-tag)

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0.25 mg / €940.00
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Complement factor D

Product Description for Complement factor D

Complement factor D.
Presentation: Purified

Properties for Complement factor D

Product Category Proteins & Growth Factors
Target Category
Quantity 0.25 mg
Synonyms Adipsin, C3 convertase activator, CFD, DF, PFD, Properdin factor D
Presentation Purified
Molecular weight 26.01 kDa
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P00746
Purity > 95 % by SDS - PAGE.
Background CFD, also known as Complement factor D preproprotein, is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. There are two antiparallel beta-barrel domains with each barrel containing six beta-strands with the same typology in all enzymes. The major difference in backbone structure between Factor D and the other serine proteases of the chymotrpsin family is in the surface loops connecting the secondary structural elements. Factor D displays different conformations of major catalytic and substrate-binding residues typically found in the chrotrypsin family.
Concentration 1.0 mg/ml (determined by bradford assay)
General Readings Ronti T. et al. (2006) Clin. Endocrinol. 64(4):355-65.Volanakis JE. et al. (1996). Protein Sci. 5(4):553-64.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human CFD, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
AA Sequence:
PPRGRILGGR EAEAHARPYM ASVQLNGAHL CGGVLVAEQW VLSAAHCLED AADGKVQVLL GAHSLSQPEP SKRLYDVLRA VPHPDSQPDT IDHDLLLLQL SEKATLGPAV RPLPWQRVDR DVAPGTLCDV AGWGIVNHAG RRPDSLQHVL LPVLDRATCN RRTHHDGAIT ERLMCAESNR RDSCKGDSGG PLVCGGVLEG VVTSGSRVCG NRKKPGIYTR VASYAAWIDS VLAVEHHHHH H
Molecular weight:
(241aa) confirmed by MALDI-TOF
Format
Buffer System:
Phosphate buffered saline (pH7.4).
Endotoxin level:
< 1.0 Eu per 1 microgram of protein (determined by LAL method)
Purity:
>95% by SDS - PAGE.
State:
Liquid purified protein
Purified
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