AR10514PU-S Cytomegalovirus Pp28

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Cytomegalovirus Pp28


Product Description for Cytomegalovirus Pp28

Cytomegalovirus Pp28.
Presentation: Purified

Properties for Cytomegalovirus Pp28

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Presentation Purified
Source E. coli
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Purity >95% pure as determined by 10% PAGE (coomassie staining).
Purification Method: Sepharose-Derived Purification.
Application Antigen in ELISA and Western blots, excellent antigen for detection of CMV with minimal specificity problems.
Background CMV belongs to the Betaherpesvirinae subfamily of Herpesviridae which includes herpes simplex virustypes 1 and 2, varicella-zoster virus, and Epstein-Barrvirus. The herpesviruses share a characteristic ability to remain latentover long periods. CMV is a double-stranded linear DNA virus with 162 hexagonal protein capsomeres surrounded by a lipid membrane. CMV has the largest genome of the herpes viruses, ranging from 230-240 kilobase pairs. Human CMV is composed of unique and inverted repeats that include the existence of 4 genome isomers caused by inversion of L-S genome components (class E). Replication may be divided into immediate early, delayed early, and late gene expression based on time of synthesis after infection. The DNA is replicated by rolling circles. In vitro, CMV replicates in human fibroblasts. 
Concentration 1.0 mg/ml

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

E.coli derived recombinant. The protein contains the CMV Pp28 (UL99) immunodominant regions.
Specificity: Immunoreactive with sera of CMV-infected individuals.
Buffer System:
25mM Tris-HCl pH 7.2, 1mM EDTA, 50% Glycerol
>95% pure as determined by 10% PAGE (coomassie staining).
Purification Method: Sepharose-Derived Purification.
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