discontinued

AR10254PU-L Deslorelin

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0.1 g / €660.00

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Deslorelin

AR10254PU-L

Product Description for Deslorelin

Deslorelin.
Presentation: Purified

Properties for Deslorelin

Product Category Proteins & Growth Factors
Quantity 0.1 g
Presentation Purified
Source Synthetic
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Purity >99.0% as determined by both RP-HPLC and SDS-PAGE analysis
Background

Deslorelin is being studied in the treatment of cancer as a way to block sex hormones made by the ovaries or testicles. It belongs to the family of drugs called gonadotropin-releasing hormone analogs. It is used for the induction of ovulation in mares. Deslorelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Continuous, prolonged administration of goserelin in males results in pituitary GnRH receptor desensitization and inhibition of pituitary secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production.

Storage

Prior to reconstitution store at RT for one month or desiccated below -18°C.
Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). 
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Source Synthetic
Description
Description:
Deslorelin is a potent LHRH/GnRH agonist has a molecular formula of C64H83N17O12, Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NHEt having a Mw of 1282.47 Dalton.
Format
Purity:
>99.0% as determined by both RP-HPLC and SDS-PAGE analysis
State:
Sterile Filtered White lyophilized (freeze-dried) powder without additives
Purified
Reconstitution:
Restore in sterile 18MΩ-cm-1 H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
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