AR51721PU-N DPPA5 / ESG1 (1-116, His-tag)

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0.25 mg / €940.00
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DPPA5 / ESG1

Product Description for DPPA5 / ESG1

DPPA5 / ESG1.
Presentation: Purified

Properties for DPPA5 / ESG1

Product Category Proteins & Growth Factors
Target Category
Quantity 0.25 mg
Synonyms Developmental pluripotency-associated 5 protein, Embryonal stem cell-specific gene 1 protein
Presentation Purified
Molecular weight 15.9 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
A6NC42
Purity > 85 % by SDS - PAGE
Background Developmental pluripotency-associated 5 proteins, also known as DPPA5, is a 116 amino acid protein that localizes to the cytoplasm and contains one KH domain. Expressed in embryonic germ (EG), primordial germ (PG) and embryonic stem (ES) cells, DPPA5 plays an important role in the maintenance of ES cell pluripotency and may be necessary for proper embryogenesis. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus.
Concentration 0.25 mg/ml (determined by Bradford assay)
General Readings
  1. Kim SK, Suh MR, Yoon HS, Lee JB, Oh SK, Moon SY, et al. Identification of developmental pluripotency associated 5 expression in human pluripotent stem cells. Stem Cells. 2005 Apr;23(4):458-62. PubMed PMID: 15790765.
  2. Pierre A, Gautier M, Callebaut I, Bontoux M, Jeanpierre E, Pontarotti P, et al. Atypical structure and phylogenomic evolution of the new eutherian oocyte- and embryo-expressed KHDC1/DPPA5/ECAT1/OOEP gene family. Genomics. 2007 Nov;90(5):583-94. Epub 2007 Oct 3. PubMed PMID: 17913455.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human DPPA5 protein, fused to His-tag at N-terminus, was expressed in E.coli.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSMGTLPAR RHIPPWVKVP EDLKDPEVFQ VQTRLLKAIF GPDGSRIPYIEQVSKAMLEL KALESSDLTE VVVYGSYLYK LRTKWMLQSM AEWHRQRQER GMLKLAEAMN ALELGPWMK
Molecular weight:
(139aa)
Format
Buffer System:
20 mM Phosphate buffer (pH 8.0) containing 10% glycerol.
Purity:
>85% by SDS - PAGE
State:
Liquid purified protein
Purified
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