AR51617PU-N DPY30 (1-99, His-tag)

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0.5 mg / €730.00
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Quick Overview

DPY30

Product Description for DPY30

DPY30.
Presentation: Purified

Properties for DPY30

Product Category Proteins & Growth Factors
Quantity 0.5 mg
Synonyms HDPY-30, Saf19, protein dpy-30 homolog
Presentation Purified
Molecular weight 13.6 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9C005
Purity > 95 % by SDS - PAGE
Background As part of the MLL1/MLL complex, DPY30 is involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. This protein may play some role in histone H3 acetylation. In a teratocarcinoma cell, it plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. DPY30 may also play an indirect or direct role in endosomal transport.
Concentration 1.0 mg/ml (determined by Bradford assay)
General Readings Xu Z., et al (2009). J. Cell Biol. 186:343-353Patel A., et al (2009). J. Biol. Chem. 284:24242-24256
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description
Description:
Recombinant human DPY30 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSMEPEQML EGQTQVAENP HSEYGLTDNV ERIVENEKIN AEKSSKQKVD LQSLPTRAYL DQTVVPILLQ GLAVLAKERP PNPIEFLASY LLKNKAQFED RN
Molecular weight:
(122aa) confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 30% glycerol, 2mM DTT
Purity:
>95% by SDS - PAGE
State:
Liquid purified protein
Purified
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