discontinued

AR10226PU-S Elcatonin

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0.2 mg / €230.00

Quick Overview

Elcatonin

AR10226PU-S

Product Description for Elcatonin

Elcatonin.
Presentation: Purified

Properties for Elcatonin

Product Category Proteins & Growth Factors
Quantity 0.2 mg
Presentation Purified
Molecular weight 3363.2 Da
Source Synthetic
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Purity > 93.9% as determined by both RP-HPLC and SDS-PAGE analysis
Background

Elcatonin is a Calcitonin derivative which is transformed from eel's calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. In addition, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.

Storage

Prior to reconstitution store at 2-8°C for one month or desiccated below -18°C.
Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Source Synthetic
Description
Description:
Elcatonin Synthetic is a single, non-glycosylated polypeptide chain containing 31 amino acids.
Molecular formula: C148H244N42O47
AA Sequence:
Ser-Asn-Leu-Ser-Thr-Asu-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Val-Gly-Ala-Gly-Thr-Pro-NH2
Biological activity:
6065 IU/mg (based on net peptide)
Format
Purity:
> 93.9% as determined by both RP-HPLC and SDS-PAGE analysis
State:
Sterile Filtered White lyophilized (freeze-dried) powder without additives
Purified
Reconstitution:
Restore in sterile 18MΩ-cm-1 H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
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