AR00044PU-N Eosinophil peroxidase

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0.2 mg / €1,070.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Eosinophil peroxidase

AR00044PU-N

Product Description for Eosinophil peroxidase

Eosinophil peroxidase.
Presentation: Purified

Properties for Eosinophil peroxidase

Product Category Proteins & Growth Factors
Target Category
Quantity 0.2 mg
Synonyms EPER, EPO, EPP, EPX
Presentation Purified
Source Eosinophils
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P11678
Purity >95% pure by SDS-PAGE.
Background Eosinophil Peroxidase, is an antimycobacterial protein that localizes to cytoplasmic granules of eosinophils and recruits bromide to generate a halogenating oxidant. EPX dependent generation of hypobromous acid causes damage to tissue during inflammatory conditions that include asthma, allergies,cancer and parasitic/helminthic infections. EPX is a major enzyme present in eosinophils and upon degranulation, becomes released into the airways of asthmatics. As a result of its cationic nature and its ability to catalyze the formation of highly toxic oxidants, EPX can induce lung injury in a JNK dependent manner.
Caution Contains human source material. No known test method can offer complete assurance that infectious agents are absent. All human source products should be handled using the same safety precautions employed when handling any potentially infectious material.
Concentration 1.925 mg/ml
Storage Store the protein at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Human Eosinophil Peroxidase.
Format
Buffer System:
20mM HEPES-NaOH, pH 8.0 containing 0.4M Sodium Chloride, 0.1mM PMSF, 0.02% Lubrol with 0.09% preservative, Bromo-nitro-dioxane/methylisothiazolone.
Purity:
>95% pure by SDS-PAGE.
State:
Liquid purified protein
Purified
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