NBC1-18871 Fumarase

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Product Description for Fumarase

Product is tested for Enzyme Immunoassay, SDS-PAGE.

Properties for Fumarase

Product Category Proteins & Growth Factors
Target Category
Quantity 0.1 mg
Synonyms HLRCC, LRCC, MCL, MCUL1, mitochondrial Fumarate hydratase
Reactivity Hu
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Swiss Prot Num:
Purity Protein
Application Western Blot, Western Blot, Western Blot
Background Fumarase (Fumarate hytdratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid (TCA), or Krebs cycle. This enzyme exists in both a cytosolic form and an N-terminal extended mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase deficiency can lead to progressive encephalopathy, cerebral atrophy and developmental delay and this enzyme also is thought to act as a tumor suppressor. Recombinant Fumarase was expressed in E.coli and was purified by conventional chromatography techniques.
Concentration 1 mg/ml
Storage Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer System:
No Preservative
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