Product Description for Geldanamycin
Properties for Geldanamycin
|Product Category||Proteins & Growth Factors|
|PDF datasheet||View Datasheet|
|Manufacturer||Acris Antibodies GmbH|
|Material safety datasheet||MSDS for Proteins (de)|
|Purity||> 98 % 98 %|
|Background||Geldanamycin is a benzoquinoid ansamycin produced by Streptomyces hygroscopicus. It binds specifically to heat shock protein HSP90 and downregulates target proteins including tyrosine kinases, steroid receptors, transcription factors and cell cycle regulatory kinases (1, 2). It induces the inactivation, destabilization and eventual degradation of HIF-1α (3).
This inhibitor is a useful tool for affinity purification of HSP-90 and HSP-90 dependent client proteins (4).
|Storage||Store the antibody (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
Avoid repeated freezing and thawing.
Protect from light!
Shelf life: One year from despatch.