discontinued

AR10475PU-L GHRH receptor (GHBP)

Search for all "GHRH receptor"

1 mg / €1,210.00

Quick Overview

GHRH receptor

AR10475PU-L

Product Description for GHRH receptor

GHRH receptor.
Presentation: Purified

Properties for GHRH receptor

Product Category Proteins & Growth Factors
Quantity 1 mg
Presentation Purified
Molecular weight 28 kDa
Source E. coli
Species (Protein) Sheep
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q28575
Purity >95.0% as determined by both RP-HPLC and SDS-PAGE analysis
Background GHBP is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized
Concentration 1.0 mg/ml (prior to lyophil.)
Storage Prior to reconstitution store at 2-8°C for one month or desiccated below -18°C.
Following reconstitution store undiluted at 2-8°C for one month
or (in aliquots) at -20°C for longer. 
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). 
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant Ovine Growth Hormone Binding Protein produced in E.coli is a single, non-glycosylated, polypeptide chain containing 237 amino acids and purified by proprietary chromatographic techniques.
AA Sequence:
The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Phe-Ser-Gly-Ser.
Format
Buffer System:
Lyophilized from a concentrated (1.0 mg/ml) solution with 0.0045mM NaHCO3
Purity:
>95.0% as determined by both RP-HPLC and SDS-PAGE analysis
State:
Sterile Filtered White lyophilized (freeze-dried) powder
Purified
Reconstitution:
Restore in sterile 18MΩ-cm-1 H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
  • LinkedIn