AR51650PU-S GLTPD1 (1-214, His-tag)

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20 µg / €300.00
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Quick Overview

GLTPD1

Product Description for GLTPD1

GLTPD1.
Presentation: Purified

Properties for GLTPD1

Product Category Proteins & Growth Factors
Quantity 20 µg
Synonyms CPTP, Glycolipid transfer protein domain-containing protein 1, MGC10334, glycolipid transfer protein domain containing 1
Presentation Purified
Molecular weight 26.8 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q5TA50
Purity > 90 % by SDS - PAGE
Background GLTPD1 mediates the intracellular transfer of ceramide-1-phosphate between organelle membranes and the cell membrane. This protein is required for normal structure of the Golgi stacks. GLTPD1 can bind phosphoceramides with a variety of aliphatic chains, but has a preference for lipids with saturated C16:0 or monounsaturated C18:1 aliphatic chains, and is inefficient with phosphoceramides containing lignoceryl (C24:0). It plays a role in the regulation of the cellular levels of ceramide-1-phosphate, and thereby contributes to the regulation of phospholipase PLA2G4A activity and the release of arachidonic acid.
Concentration 0.25 mg/ml (determined by Bradford assay)
General Readings Simanshu D.K., et al. (2013) Nature 500:463-467.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human GLTPD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSMDDSETG FNLKVVLVSF KQCLDEKEEV LLDPYIASWK GLVRFLNSLG TIFSFISKDV VSKLRIMERL RGGPQSEHYR SLQAMVAHEL SNRLVDLERR SHHPESGCRT VLRLHRALHW LQLFLEGLRT SPEDARTSAL CADSYNASLA AYHPWVVRRA VTVAFCTLPT REVFLEAMNV GPPEQAVQML GEALPFIQRV YNVSQKLYAE HSLLDLP
Molecular weight:
(237aa) confirmed by MALDI-TOF
Format
Buffer System:
PBS, pH7.4 containing 50% glycerol, 1mM DTT
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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