AR05227PU-L Glutathione

Search for all "Glutathione"

1 mg / €400.00

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Product Description for Glutathione


Properties for Glutathione

Product Category Proteins & Growth Factors
Quantity 1 mg
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Application Immunohistochemistry on frozen and paraffin sections.
Background Glutathione is a small peptide composed of three amino acids: cysteine, glutamic acid, and glycine and is present in tissues in concentrations as high as one millimolar. It contains an unusual peptide linkage between the amine group of cysteine and the carboxyl group of the glutamate side chain. Glutathione is involved in detoxification, it binds to toxins, such as heavy metals, solvents, and pesticides, and transforms them into a form that can be excreted in urine or bile. It is also an important antioxidant, helping to maintain the -SH groups of proteins in their reduced form.

Chronic functional glutathione deficiency is associated with glucose 6-phosphate dehydrogenase deficiency, immune disorders, an increased incidence of malignancies, and in the case of HIV disease, probably accelerated pathogenesis of the disease. Acute manifestations of functional glutathione deficiency can be seen in those who have taken an overdosage of acetaminophen (paracetamol). This results in depletion of glutathione in the hepatocytes, leading to liver failure and death.
Concentration 1.0mg/ml
Storage Store the protein at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Glutathione-G-BSA Conjugate.
Lyophilised purified protein
1.0ml distilled water containing 0.1% merthiolate.
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