Product Description for Glycogen Phosphorylase
Properties for Glycogen Phosphorylase
|Product Category||Proteins & Growth Factors|
|Molecular weight||97 kDa|
|PDF datasheet||View Datasheet|
|Manufacturer||Acris Antibodies GmbH|
|Material safety datasheet||MSDS for Proteins (de)|
|Purity||> 85 % Greater than 85.0% as determined by:
(a) Analysis by RP-HPLC
(b) Analysis by reducing and non-reducing SDS-PAGE Silver Stained
|Application||Immunoassays and Western blot.|
|Background||Glycogen Phosphorylase is an enzyme that catalyzes the degradation of Glycogen in animals by releasing glucose-1-phosphate from the terminal alpha-1,4-glycosidic bond.
This enzyme exists in two forms: an active phosphorylated form (Phosphorylase A) and an inactive un-phosphorylated form (Phosphorylase B).
Both a and b forms of phosphorylase exist as homodimers. In mammals, the major isozymes of glycogen phosphorylase are found in muscle, liver and brain tissue. Glycogen Phosphorylase- a sensitive marker for the AMI diagnosis within 4 hours after the onset of chest pain. It has also been shown that GPBB is increased in a considerable proportion of AMI patients within 2-3 hours from chest pain onset. GPBB is increased early in patients with unstable angina. Glycogen Phosphorylase can also be used as a sensitive marker for the detection of peri-operative myocardial ischaemia and infarction in patients undergoing coronary artery bypass grafting.
|Storage||Recombinant Glycogen Phosphorylase, although stable at 10°C for 1 week, should be stored below -18°C.
Please avoid freeze-thaw cycles.
Shelf life: one year from despatch.