Product Description for Growth Hormone Antagonist
Properties for Growth Hormone Antagonist
|Product Category||Proteins & Growth Factors|
|Molecular weight||22 kDa|
|PDF datasheet||View Datasheet|
|Manufacturer||Acris Antibodies GmbH|
|Material safety datasheet||MSDS for Proteins (de)|
|Purity||>98.0% as determined by both RP-HPLC and SDS-PAGE analysis.
Purification Method: proprietary chromatographic techniques.
GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
|Storage||Prior to reconstitution store at 2-8°C for one month or desiccated below -18°C.
Following reconstitution and filter sterilization store undiluted at 2-8°C for one month
or (in aliquots) at -20°C for longer.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.