Product Description for GTF3C6
Properties for GTF3C6
|Product Category||Proteins & Growth Factors|
|Synonyms||C6orf51, General transcription factor 3C polypeptide 6, TFIIIC35, bA397G5.3|
|Molecular weight||26.4 kDa|
|PDF datasheet||View Datasheet|
|Manufacturer||Acris Antibodies GmbH|
|Material safety datasheet||MSDS for Proteins (de)|
|Purity||> 85 % by SDS - PAGE|
|Background||RNA polymerases are unable to initiate RNA synthesis in the absence of additional proteins called general transcription factors (GTFs). GTFs assemble in a complex on the DNA promoter and recruit the RNA polymerase. GTF3C family proteins (e.g., GTF3C1, MIM 603246) are essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA (MIM 180420), tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin.|
|Concentration||0.5 mg/ml (determined by BRADFORD assay)|
|General Readings||Dumay-Odelot,H., et al. (2007) J. Biol. Chem. 282 (23), 17179-17189|
|Storage||Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.