AR51586PU-S HCV-Core (1-120, His-tag)

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0.1 mg / €300.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

HCV-Core

Product Description for HCV-Core

HCV-Core.
Presentation: Purified

Properties for HCV-Core

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms Human Hepatitis C Virus E2 protein fragment, Polyprotein
Presentation Purified
Molecular weight 15.7 kDa
Source E. coli
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
B3TKP0
Purity > 85 % by SDS - PAGE
Background HCV-Core protein packages viral RNA to form a viral nucleocapsid, and promotes virion budding. It modulates viral translation initiation by interacting with HCV IRES and 40S ribosomal subunit and also regulates many host cellular functions such as signaling pathways and apoptosis. HCV-Core prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation.
Concentration 0.5 mg/ml (determined by Bradford assay)
General Readings Taylor D.R., et al. (2001) J. Virol. 75:1265-1273Kalliampakou K.I., et al. (2015) J. Gen. Virol. 86:1015-1025
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description
Description:
Recombinant Hepatitis C virus Core protein, fused to His-tag at N-terminus, was expressed in E.coli.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MSTNPKPQRK TKRNTNRRPQ DVKFPGGGQI VGGVYLLPRR GPRLGVRATR KTSERSQPRG RRQPIPKARR PEGRTWAQPG YPWPLYGNEG CGWAGWLLSP RGSRPSWGPT DPRRRSRNLG
Molecular weight:
(140aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
Purity:
>85% by SDS - PAGE
State:
Liquid purified protein
Purified
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