Product Description for Heparin Binding EGF-like growth factor (HB-EGF)
Properties for Heparin Binding EGF-like growth factor (HB-EGF)
|Product Category||Proteins & Growth Factors|
|Synonyms||DTR, Diphteria toxin receptor|
|Molecular weight||9.7 kDa|
|PDF datasheet||View Datasheet|
|Manufacturer||Acris Antibodies GmbH|
|Material safety datasheet||MSDS for Proteins (de)|
|Purity||> 95 %|
|Add. information||Centrifuge the vial prior to opening.!|
|Background||HB-EGF is an EGF related growth factor that signals through the EGF receptor, and stimulates the proliferation of smooth muscle cells (SMC), fibroblasts, epithelial cells, and keratinocytes. HB-EGF is expressed in numerous cell types and tissues, including vascular endothelial cells and SMC, macrophages, skeletal muscle, keratinocytes, and certain tumor cells. The ability of HB-EGF to specifically bind heparin and heparin sulfate proteoglycans is distinct from other EGF-like molecules, and may be related to the enhanced mitogenic activity, relative to EGF, that HB-EGF exerts on smooth muscle cells. The human HB-EGF gene encodes a 208 amino acid transmembrane protein, which can be proteolytically cleaved to produce soluble HB-EGF.|
|Storage||Store the lyophilized protein at -20 °C.
Reconstituted human CTGF should be stored in working aliquots at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.