AR10547PU-L Hepatitis B E / HBeAg

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1 mg / €570.00

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Hepatitis B E / HBeAg


Product Description for Hepatitis B E / HBeAg

Hepatitis B E / HBeAg.
Presentation: Purified

Properties for Hepatitis B E / HBeAg

Product Category Proteins & Growth Factors
Quantity 1 mg
Presentation Purified
Source E. coli
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Purity >95% pure as determined by 10% PAGE (coomassie staining).
Purification Method: GS-4B Sepharose-Affinity Purification.
Application Antigen in ELISA and Western blots, excellent antigen for detection of HBV with minimal specificity problems.
Background Hepatitis B is one of a few known non-retroviralviruses which employ reverse transcriptionas a part of its replication process. (HIV, a completely unrelated virus, also uses reverse transcription, but it is a retrovirus.) HBV invades the cell by binding to surface receptor and become internalized. The viral core particles then migrate to the hepatocyte nucleus and the partially double-stranded, relaxed circular genomes (RC-DNA) are repaired to form a covalently closed circular DNA (cccDNA), which is the template for viral genomic and sub-genomic RNAs by cellular RNA polymerase II. Of these, the pregenomic RNA (pgRNA is selectively packaged into progeny capsids and is then reverse-transcribed into new RC-DNA. The core can either bud into the endoplasmic reticulum to be enveloped or exported from the cell or recycled back into the genome for conversion to cccDNA. 
Concentration 1 mg/ml
Storage Protein is shipped at ambient temperature.
Upon arrival, Store at -20°C. 
Please avoid freeze-thaw cycles. 
Shelf life: One year from despatch.
E.coli derived recombinant. The protein contains the HBV HBe immunodominant region.
Specificity: Immunoreactive with sera of HBV-infected individuals.
>95% pure as determined by 10% PAGE (coomassie staining).
Purification Method: GS-4B Sepharose-Affinity Purification.
25mM Tris-HCl pH 8.0, 1.5M Urea, 50% Glycerol.
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