discontinued

AR10595PU-S Hepatitis C Virus Core Genotype 2b (2-119)

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0.1 mg / €280.00

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Hepatitis C Virus Core Genotype 2b

AR10595PU-S

Product Description for Hepatitis C Virus Core Genotype 2b

Hepatitis C Virus Core Genotype 2b.
Presentation: Purified

Properties for Hepatitis C Virus Core Genotype 2b

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Presentation Purified
Source E. coli
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Purity >95% pure as determined by 10% PAGE (coomassie staining). 
Purification Method: Proprietary chromatographic technique.
Application HCV Core Genotype-2b antigen is suitable for ELISA and Western blots, excellent antigen for detection of HCV with minimal specificity problems.
Background

HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae.
HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).

Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Description
Description:
The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 1691-1710, 1712-1733 & 1921-1940, fused with a GST tag at N-terminus. 
Specificity: Immunoreactive with sera of HCV-infected individuals.
Format
Buffer System:
25mM Tris-HCl, pH 8.0, 1.5M Urea, 0.2% Triton-X and 50% Glycerol 
Purity:
>95% pure as determined by 10% PAGE (coomassie staining). 
Purification Method: Proprietary chromatographic technique.
State:
Purified
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