Product Description for Hepatitis C Virus NS5 Genotype 1
Properties for Hepatitis C Virus NS5 Genotype 1
|Product Category||Proteins & Growth Factors|
|PDF datasheet||View Datasheet|
|Manufacturer||Acris Antibodies GmbH|
|Material safety datasheet||MSDS for Proteins (de)|
|Purity||>95.0% pure as determined by 10% PAGE (coomassie staining).
Purification Method: S-Sepharose > Ceramic Hydroxyapatite > Affinity Purification.
|Application||Antigen in ELISA and Western blots, excellent antigen for detection of HCV with minimal specificity problems.|
|Background||HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae.
HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.