AR03028PU-S Herbimycin A

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0.1 mg / €240.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Herbimycin A

Product Description for Herbimycin A

Herbimycin A.
Presentation: Purified

Properties for Herbimycin A

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Presentation Purified
Molecular weight 574.3
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Purity > 98 % 98%
Background Herbimycin A, a benzoquinoid ansamycin antibiotic, irreversibly and selectively inhibits tyrosine kinases by reacting with thiol groups (1,2). It is effective on Src, Yes, Fps, Ros, Abl and ErbB oncogene products (1-3) and inhibits thrombin-induced tyrosine phosphorylation of phospholipase C (4).
Protocols 1. Uehara Y.,and Fukazawa H. (1991) Methods Enzymol. 201: 370.
2. Fukazawa H., et al. (1991) Biochem. Pharmacol. 42: 1661.
3. Satoh T., et al.(1992) J.Biol.Chem. 267: 2537.
4. Weiss R., and Nuccitelli R. (1992) J.Biol.Chem. 267:5608.
Storage Store the antibody (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
Avoid repeated freezing and thawing.
Protect from light!
Shelf life: One year from despatch.
Source Synthetic
Formula: C30H42N2O9
Molecular weight:
>98% 98%
Lyophilized solid; yellow
Soluble in DMSO and ethanol (1 mg/ml)
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