NB110-81565 Herbimycin A

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0.1 mg / €340.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Herbimycin A

NB110-81565

Product Description for Herbimycin A

Herbimycin A.

Properties for Herbimycin A

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Add. information Synthetic Herbimycin A
98% pure
Soluble in DMSO and ethanol (1mg/mL)
Lyophilized solid; yellow
Application , Synthetic Herbimycin A 98% pure Soluble in DMSO and ethanol (1mg/mL) Lyophilized solid; yellow
Background Herbimycin A, a benzoquinoid ansamycin antibiotic, irreversibly and selectively inhibits tyrosine kinases by reacting with thiol groups (1,2). It is effective on Src, Yes, Fps, Ros, Abl and ErbB oncogene products (1-3) and inhibits thrombin-induced tyrosine phosphorylation of phospholipase C (4).
General Readings
  1. Uehara Y.,and Fukazawa H. (1991) Methods Enzymol. 201: 370.
  2. Fukazawa H., et al. (1991) Biochem. Pharmacol. 42: 1661.
  3. Satoh T., et al.(1992) J.Biol.Chem. 267: 2537.
  4. Weiss R., and Nuccitelli R. (1992) J.Biol.Chem. 267:5608.
Storage Store at -20C. Avoid freeze-thaw cycles.
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