discontinued

AR10234PU-S Histrelin

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1 mg / €230.00

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Histrelin

AR10234PU-S

Product Description for Histrelin

Histrelin.
Presentation: Purified

Properties for Histrelin

Product Category Proteins & Growth Factors
Quantity 1 mg
Presentation Purified
Source Synthetic
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Purity > 99.0% as determined both RP-HPLC and SDS-PAGE analysis
Background Histrelin is a hormone similar to one normally released from the hypothalamus gland in the brain. Histrelin works by decreasing the amount of estrogen and testosterone in the blood. Suppressing estrogen can cause thinning of the bones or slowing of their growth. Histrelin acetate is a potent LHRH agonist which stimulates LH and FSH release and inhibits the actions of sex steroids on the male and female reproductive tracts. After a transient increase, continuous administration results in down regulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis. Histrelin potency in vivo and in vitro is similar to that of the D-Trp6-containing analog. Especially because of its high water Reconstitution and greater lipophilic character, it appears promising for clinical application.
Storage

Prior to reconstitution store at 2-8°C for one month or desiccated below -18°C.
Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Source Synthetic
Description
Description:
Histrelin has a Molecular formula of C66H86N18O12
AA Sequence:
Pyr-His-Trp-Ser-Tyr-D-His(Bzl)-Leu-Arg-Pro-NHEt
Format
Purity:
> 99.0% as determined both RP-HPLC and SDS-PAGE analysis
State:
Sterile Filtered White lyophilized (freeze-dried) powder without additives
Purified
Reconstitution:
Restore in sterile 18MΩ-cm-1 H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
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