HPRT1 / HPRT (1-218, His-tag) - AR09522PU-L

Product Description for HPRT1 / HPRT

HPRT1 / HPRT.
Presentation: Purified

Product Category	Proteins & Growth Factors
Target Category	HPRT1 / HPRT antibody
Quantity	0.5 mg
Synonyms	HGPRT, HGPRTase, Hypoxanthine-guanine phosphoribosyltransferase
Presentation	Purified
Molecular weight	26.7 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	Acris Antibodies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: P00492
Purity	> 95 % by SDS – PAGE
Background	Hypoxanthine-guanine phosphoribosyltransferase, also known as HPRT1 has a central role in the generation of purine nucleotides through the purine salvage pathway. The enzyme primarily functions to salvage purines from degraded DNA to renewed purine synthesis. In this role, it acts as a catalyst in the reaction between guanine and phosphoribosyl pyrophosphate to form GMP.
Concentration	0.5 mg/ml (determined by Bradford assay)
General Readings	Hladnik U., et al. (2008) Arch Neurol. 65(9):1240-3.
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human HPRT1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MATRSPGVVI SDDEPGYDLD LFCIPNHYAE DLERVFIPHG LIMDRTERLA RDVMKEMGGH HIVALCVLKG GYKFFADLLD YIKALNRNSD RSIPMTVDFI RLKSYCNDQS TGDIKVIGGD DLSTLTGKNV LIVEDIIDTG KTMQTLLSLV RQYNPKMVKV ASLLVKRTPR SVGYKPDFVG FEIPDKFVVG YALDYNEYFR DLNHVCVISE TGKAKYKA` Molecular weight: (238aa), confirmed by MALDI-TOF
Format	Buffer System: 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol Purity: >95% by SDS – PAGE State: Liquid purified protein Purified